Be confused by a NCA result
Wei Wang
on 5 Apr 2020
Latest activity Edit by Rick Paxson
on 5 Apr 2020
Hi, all friends
I am dealing with a confusing NCA result. As this result shows, AUC_infinity=0.8537 (μg*h/mL), DM=1 (mg). CL should be equal to DM/AUC_infinity but why is the calculated result 2.4491? There is no dimension along with value so I do not know if I ignore anything.
Does any one can handle with this situation? Thanks very much. I also post my used data (i.v.).
2 Comments
Time Descending
Oh, sorry for this issue, I make something wrong! I should have cleared the dose I used before and added a dose of 1 mg to timepotin 0 h. After that, calculated CL is 1.1466.
Hello Wei Wang,
I am glad you found the problem.
Best,
-Rick Paxson
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