Endothelial Cell Model
An interactive GUI for an endothelial cell model.
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Vascular endothelial cells (ECs) modulate smooth muscle cells (SMC) contractility, assisting in vascular tone and regulation. Our lab has created a detailed model for this cell that integrates plasma membrane electrophysiology and calcium dynamics to investigate EC responses to various stimuli. It also expands on previous formulations by including more detailed transmembrane current descriptions.
To assist in disseminating our model to as many people working in our field as possible we have designed an interactive graphical user interface (GUI) that allows for a user to investigate various phenomena relating to EC behavior without having to understand the complicated coding or math formulations behind them.
Further information on our modeling efforts can be found at: https://tsoukias.fiu.edu/
Original Endothelial Cell Model by Haroldo Silva:
A mathematical model of plasma membrane electrophysiology and calcium dynamics in vascular endothelial cells
Haroldo S. Silva, Adam Kapela, and Nikolaos M. Tsoukias
American Journal of Physiology-Cell Physiology 2007 293:1, C277-C293
Cite As
Asad Mirza (2026). Endothelial Cell Model (https://github.com/DThornz/Endothelial-Cell-Model), GitHub. Retrieved .
General Information
- Version 1.16 (5.07 MB)
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View License on GitHub
MATLAB Release Compatibility
- Compatible with R2018a and later releases
Platform Compatibility
- Windows
- macOS
- Linux
Versions that use the GitHub default branch cannot be downloaded
| Version | Published | Release Notes | Action |
|---|---|---|---|
| 1.16 | Fixed MATLAB Release Compatibility listing |
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| 1.15 | Updated description |
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| 1.1 | Added mlapp and exe version of model. |
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| 1.0.1 | Edited title |
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| 1.0.0 |
