SD of the concentration-time AUC after fitting


can we directly get the SD of the concentration-time AUC after fitting in Simbiology?

Jeremy Huard
Jeremy Huard on 16 Sep 2019

Hi Deni,

let me describe my understanding: you perform data fitting in SimBiology and compute the AUC of one response. Now you would to estimate the uncertainty of this AUC be computing its standard deviation. Is this correct?

If so, one idea could be to use sbiopredictionci to compute the confidence interval of the prediction. The resulting object has a property Results, which contains the confidence interval. You can then compute its AUC using the trapezoidal method (function trapz ). This might already be what you want. But if you explicitely need the standard deviation, you might be able to derive it from the confidence interval.

On a side note, this question fits better the Answers section of this webpage that the Discussions section. Could you please post there next time?

Thanks, Jérémy

Deni Hardiansyah
Deni Hardiansyah on 16 Sep 2019

Hi Jeremy,

Thank you very much for your answer, yes, I would like to calculate the SD of the AUC of one response after fitting this response in Simbiology. I will try your method.

PS: Okay I will post over there next time.

Thanks, Deni

Tags

No tags entered yet.