NO. You don't use vpa. No need to do that, and in fact, vpa would be the wrong tool to use anyway.
This works fine though.
a = sym('73167176531330624919225119674426574742355349194934')
>> a + 2
You could also have used my VPI toolbox, but syms are faster than VPI. (That was not always the case as I recall, when I was first developing VPI.) And since you have the symbolic toobox anyway, just use it, properly, as I did there.