How to compare two O-QPSK modulated digitals signals?

Hello,

I am working on wireless sensors project and I am trying to simulate a transmission between two nodes. So let's say I have two nodes which transmit the message to each other, i.e. node 1 transmits to node 2 and then node 2 transmits to node 1. Let's say the message is exactly the same and the difference between packet being transmitted is just Source/Destination Adress as well as Frame Check Sequence Field(FCS) of MPDU. The message is being generated and encoded into signal wave.

Now, without demodulation process and looking only at the waveforms of transmitted signals is there any way to distinguish two signals and classify them as "signal 1" and "signal different from signal 1"? Is there also a way to extract bits from the signal ?

For example possibly by converting it to frequency domain by looking at the amplitude or phase spectrum of the signal?

Or may be it is achievable after certain number of iterations so enough data can be sampled and thus pattern can be drawn?

Please share your ideas or suggestions.