Change in matrix without re-writing

So if I have a 2x4 matrix, how do I change a number in that matrix without having to re-write the entire matrix?
M = [ 1 3 5 2
-1 0 1 7];
(M is one big matrix, I'm sorry but I'm quite new here) If I wanted to change the 7 to a 8 for instance, what would be the fastest way?
Thanks

 Accepted Answer

Rand - since the 7 is in the fourth column of the second row, then the easiest way to change this to an 8 is as follows
M(2,4) = 8;

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