How can I do Jacobian with complicated equation?

syms t real
x = sym('x', [4,1],'real');
y = x(3:4);
O = sym('O', [2,1],'real');
% L is equation of x,O
f1 = jacobian(L, y);
f2 = jacobian(L, y);
matlabFunction(f2, 'file','func_f2','vars',{t,x,O});

If L is a simple equation of x and O, it can be solved in few seconds.

My problem is my L equation is too complicate, matlab ran for 2 days and didn't get answered yet.

I tried

L = simplify(L)

But it can't be solved, matlab out of memory.

What can I do?

[Githin John]

Can you share what the function L is so that I can reproduce the issue?