Advanced Pharmacokinetics and Toxicology
Last updated: 10/25/2016
Author Information
Professor Jonghan Kim
Northeastern University
Course Details
Description
This course is focused on expanding prior basic pharmacokinetics to more advanced topics required for specialized work in research, clinical, and industrial settings. Through training of pharmacokinetic modeling/simulation software, SimBiology, students will become familiar with various analyses and modeling techniques including compartmental and physiologic models, pharmacokinetic-pharmacodynamic analyses and toxicokinetic-toxicodynamic assessments.
The course consists of four sections:
- The first section is dedicatd to comprehensive understanding of fundamental concepts of pharmacokinetics and its applications in pharmaceutical sciences and preclinical and clinical pharmacology.
- The second section provides hands-on training for modeling/analysis of pharmacokinetics and pharmacodynamics using modeling-simulation software.
- The third section is devoted to paper presentations in journal club style along with toxiology lectures.
- The last section is given by guest lecturers to provide industrial perspective in pharmacokinetics and toxicology.
The courseware content provided here belongs to the first section of this course.
Original Course Documents
Source
file URL
Course Contents
Module 1
Module 2
Module 3
Module 4
Textbooks
1- Gabrielsson and Weiner, Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, 4th edition, Swedish Pharmaceutical Press, 2007.
2- Fanchi, Math Refresher for Scientists and Engineers, 3rd edition, Wiley, 2006.
3- Rowland and Tozer, Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 4th edition, Lippincott Williams & Wilkins, 2010.
Resources
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